Department of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, P.R. China
Research Article
Diagnostic Value of Multimodal Ultrasound in Cytological Diagnosis of Indeterminate Thyroid Nodules
Author(s): Ruijuan Huang*, Shuzhen Cong, Yanyan Liang and Zhenyi Lin
Background: This study aimed to investigate the discriminative diagnostic potential of multimodal Ultrasound (US) for thyroid nodules displaying Indeterminate Cytological (IC) characteristics.
Methods: A total of 61 thyroid nodules (Bethesda III/IV/V) that underwent both fine needle aspiration biopsy and surgical intervention were examined, comprising 37 malignant and 24 benign nodules. Distinctions in sonographic features between benign and malignant nodules were evaluated. Logistic regression analysis was conducted to establish prediction models utilizing conventional US, Superb Microvascular Imaging (SMI), Ultrasound Elastography (UE), and multimodal US. The assessment of sensitivity, specificity, and accuracy in identifying malignant thyroid nodules with IC was carried out for conventional US, SMI, UE, and multimodal US. Receiver Operati.. View more»