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Katsuyuki Nakajima
Katsuyuki Nakajima
Laboratory of Clinical Nutrition and Medicine, Kagawa Nutrition University,
Tokyo
Japan
Publications
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Review Article
A Proposal of the New Mechanism on Remnant Lipoprotein Formation and Clearance after Food Intake
Author(s): Katsuyuki Nakajima and Akira TanakaKatsuyuki Nakajima and Akira Tanaka
To understand the mechanism of plasma TG increase after food intake, the characteristics of remnant lipoproteins in postprandial plasma and the role of lipoprotein lipase (LPL) were investigated. The accumulation of TG in remnant lipoproteins (RLP-TG) is caused by the unchanged levels of LPL activity for hydrolysis of chylomicrons and VLDL when overloaded at endothelium after food intake. This review proposed a new hypothesis on the metabolism of plasma TG-rich lipoprotein based on the no-change of LPL activity at endothelium after food intake and the discovery of RLP-LPL complex in postprandial plasma. .. View More»
DOI: 10.4172/2329-8847.1000173