Gerontology & Geriatric Research

The suppressive effect of organism senescence on cancers

2^nd International Conference on Geriatrics & Gerontology

August 24-26, 2015 Toronto, Canada

Alvaro Macieira-Coelho

French National Institute of Health (INSERM), France

Posters-Accepted Abstracts: J Gerontol Geriat Res

Abstract:

Most scientific literature reports that aging favors the development of cancers. Each type of cancer, however, initiates and evolves differently and their natural history can start much earlier in life before their clinical manifestations. The incidence of cancers is spread throughout human life span and is the result of pre and post natal aggressions, individual susceptibility, developmental changes that evolve continuously throughout an individualâ??s life and time of exposure to carcinogens. Finally, during human senescence the incidence declines for all cancers. Frequently, the progression of cancers is also slower in aged individuals. There are several possible explanations for this decline at the tissue, cell and molecular levels which will be described. It is time to ask why some tumors are characteristic of either the young, the aged or during the time of a decline in the reproductive period and finally why the incidence of cancers declines late during senescence of human beings. These questions need to be addressed before the origin of cancers can be understood.

Biography :

Email: macieiracoelho@gmail.com