Journal of Nutritional Disorders & Therapy

The science behind citicoline to protect against neurodegenerative processes and maintaining normal cognitive function

JOINT EVENT: 13^th International Congress on Advances in Natural Medicines Nutraceuticals & Neurocognition & 14^th International Conference on Clinical Nutrition

July 27-29, 2017 Rome, Italy

Karen E Todd

Kyowa Hakko, USA

Posters & Accepted Abstracts: J Nutr Disorders Ther

Abstract:

Statement of the Problem: The human brain is under constant attack by various factors, including environmental pollution, internal toxicity, stress and lack of nutrients due to poor diet. As we age, communication between neurons decreases and affects memory, focus, attention, recall and mental energy. Critical to brain function is citicoline, or CDP choline. The compound is comprised of cytidine and choline, with the former crucial for proper absorption of choline. In the brain, citicoline promotes the production of phosphatidylcholine (phospholipids), which make up ~30% of brain tissue, aid in neural communication and provide essential protection for neurons. The body obtains choline naturally through foods such as eggs and meat. But as we age, the body loses some of its ability to absorb choline. Methodology & Orientation: Numerous scientific studies have shown that daily supplementation of citicoline may improve brain function for subjects including healthy adolescent males, healthy middle-aged women and the elderly. Findings: Clinical trials have shown that a branded form of citicoline�??Cognizin®�??may be effective in combating the effects of certain neurodegenerative processes. Studies also show Cognizin® may aid in maintaining normal cognitive function with aging and point to its ability to act as an antioxidant in preserving normal healthy visual function. This form of citicoline has been shown to protect neural tissue from the ravages of free radical damage and is the only form approved for use within Europe as a dietary supplement ingredient.