Nicole Angelique L Sanchez1, Ma Aussielita L Lit2 and Roden C Yumol3
1University of the Philippines Los Baños, Philippines 2Analytical Solutions and Technical Services Laboratory, Philippines 3Shalom Crest Wizard Academy, Philippines
Posters-Accepted Abstracts: J Food Process Technol
Physalis angulata is widely distributed in the agricultural farms and fruit orchards in the Philippines and commercially grown in other countries like Brazil. Commonly known as wild gooseberries, it is popularly used in traditional medicine as anticoagulant, anti-leucemic, anti-spasmodic, anti-inflammatory and as food. The plant was studied to determine if Physalis angulata can be an herbal oral ProVac for infectious diseases caused by food-borne pathogens. The phytochemical profile of the plant extract was determined using the method of Samy et. al (2008). Antimicrobial assay using the Tube Dilution and Filter Paper Disc Assay methods were done after Gel Permeation Chromatography (GPS) and Solid Phase Extraction (SPE) clean-up and concentration procedures. Fractionated extracts from Physalis angulata showed that the alkaloids, terpenoids, cardiac glycosides and sterols present inhibited the growth of Listeria monocytogenes, Salmonella typhimurium and Escherichia coli. Results of Ames test showed that the combined fractionated extracts exhibited no mutagenic effect against Salmonella typhimurium TA 98. Testing of partially purified herbal extract of Physalis angulata confirmed its antimicrobial activity against all food pathogens tested. In vitro and in vivo studies have to be undertaken to elaborate its medicinal properties prior to development of Physalis angulata for drug and vaccine.
Nicole Angelique L Sanchez has completed her Bachelor of Science in Biology major in Microbiology from the University of the Philippines Los Baños. She was also an exchange student in Michigan State University (MSU) last January to April 2013 and the University of Tsukuba last March to September 2014. She has been active in research since her high school years and won first place in the INTEL Philippine Science Fair held at Subic on February 2009. She plans to pursue her graduate studies in the University of the Philippines.