Journal of Clinical & Experimental Pharmacology

Molecular and phytochemical fingerprinting of anti cancer drug yielding plants in south India

2^nd International Conference and Exhibition on Pharmacology and Ethnopharmacology

May 02-04, 2016 Chicago, USA

John De Britto Alexsis

Manonmaniam Sundaranar University, India

Scientific Tracks Abstracts: Clin Exp Pharmacol

Abstract:

Studies were performed to select the superior genotypes based on intra-specific variations, caused by phytogeographical, climatic and edaphic parameters of three anti cancer drug yielding mangrove plants such as Acanthus ilicifolius L., Calophyllum inophyllum L. and Excoecaria agallocha L. using ISSR (Inter Simple Sequence Repeats) markers and phytochemical analysis such as preliminary phytochemical tests, TLC, HPTLC, HPLC and antioxidant tests. The plants were collected from five different geographical locations of the East Coast of south India. Genetic heterozygosity, Nei�??s gene diversity, Shannon�??s information index and Percentage of polymorphism between the populations were calculated using POPGENE software. Cluster analysis was performed using UPGMA algorithm. AMOVA and correlations between genetic diversity and soil factors were analyzed. Combining the molecular and phytochemical variations superior genotypes were selected. Conservation constraints and methods of efficient exploitation of the species are discussed.

Biography :

Alexis John De Britto has completed 30 years of teaching and 25 years of research in the field of molecular biology, phytochemistry and ethnopharmacology. He has published papers in these areas of research in national and international journals and carried out major research projects funded by Government of India.

Email: bjohnde@yahoo.co.in