Clinical Microbiology: Open Access

Identification of uropathogenic bacteria and their antibiotic susceptibility patterns among the population of district Dir Lower, Pakistan

8^th CLINICAL MICROBIOLOGY CONFERENCE

October 26-28, 2017 | Paris, France

Atta Ur Rahman, Shehzad Ahmmad, Fazal Rahim, Rafiq Hussain Shah and Obaid Ur Rahman

Hazara University, Pakistan

Posters & Accepted Abstracts: Clin Microbiol

Abstract:

Urinary tract infections (UTIs) are the most common bacterial infections in human beings. UTIs caused by bacteria have been showing an increasing trend, despite the use of appropriate antibiotics. Resistance to antibiotics is due to irrational use, which is increasing day by day. The current study was conducted to identify uropathogens and antibiotic susceptibility pattern of microbial agents that Cause UTIs. For this purposes, a total of 145 urine sample were collected from both the males and females in district Dir Lower, KPK. The urine samples were cultured and all the positive samples were identified through biochemical tests. Out of these 145 samples, 83 (57.2%) samples showed significant growth. Out of a total 83 (57.2%) isolates, 71 (85.5%) showed growth for gram negative and 12 (14.5%) showed growth for gram positive bacteria. The prevalence of UTIs was found to be higher in female patients, i.e., 56 (67.5%) than in males, which were 27 (32.5%). The most prevalent uropathogenic bacteria was Klebsiella pneumoniae 33 (39.7%) followed by Escherichia coli 23 (27.7%), Pseudomonas aeruginosa 9 (10.8%), Staphylococcus aureus 8 (9.6%), Proteus mirabilis 6 (7.2%) and Staphylococcus saprophyticus 4 (4.8%). The antibiotic susceptibility tests were done. K. pneumonia showed the highest sensitivity 100% to imipenem, 78.7% to fosfomycin and showed a resistance of 100% to cefuroxime and 94% to ciprofloxacin. Similarly, the E. coli showed highest sensitivity to imipenem (100%), fosfomycin and nitrofurantoin (78.2% both), and high resistance to ciprofloxacin and cefuroxime, i.e., a resistance of 100%. Imipenem was found the most susceptible antibiotic while pathogens showed highest resistance to cefuroxime and ciprofloxacin.