Journal of Advanced Chemical Engineering

Design of highly selective and ultrasensitive Schiff base sensors for colorimetric and fluorimetric detection of metal ions

Joint Event 19^th European Organic Chemistry Congress 10^th International Conference on Physical and Theoretical Chemistry

November 07, 2023 | Webinar

Kalyan Sundar Ghosh, Shivani Sharma and Ankita Sharma

National Institute of Technology Hamirpur, India

Scientific Tracks Abstracts: J Adv Chem Eng

Abstract:

Schiff base probes were designed and synthesized for highly selective detection of Al3+, Cu2+ and Co2+ through fluorimetric and colorimetric methods. A distinct color change was noticed in case of the colorimetic probe of Co2+. Metal-probe stoichiometry in respective complexes was determined from Job’s plots and ESIMS. The effect of pH and response time in sensing was also determined. Reversibility in the metal ion binding by the probes was also tested using EDTA. Observed optical changes due to binding between probes and metal ions were supported by density functional theory (DFT). Sensing of metal ions by the probes was based on alterations in internal charge transfer (ICT) and photo-induced electron transfer (PET) process in probe molecules. Probes were also used for detection of metal ions on paper strips, in vivo detection and cellular imaging. Logic gates were constructed for the detection of cations.

Biography :

Kalyan Sundar Ghosh is presently serving as an Associate Professor at Department of Chemistry, National Institute of Technology Hamirpur, Himachal Pradesh, India, where he is working since 2012. His research interests are primarily focused on the design and development of chemo and biosensors, studies on protein aggregation and its inhibition. He has authored more than 50 publications in international journals of repute and have h-index of 24. He was awarded doctoral degree in Chemistry from Indian Institute of Technology Kharagpur, India. He had also worked as Postdoctoral Associate in State University of New York, Albany and University of Maryland, College Park. Five students have already completed their doctoral dissertation under his supervision and few more are working presently.