Journal of Nutritional Disorders & Therapy

Association between cerebral perfusion and neuropsychiatric manifestations in a celiac patient under a gluten free diet

Joint Event on Advances in Neonatal and Pediatric Nutrition & 14^th International Congress on Advances in Natural Medicines, Nutraceuticals & Neurocognition

July 19-21, 2018 | London, UK

Juliana J Schmidt, Guilherme J. Schmidt, Julio C. Tolentino, Eunice N. Simões, Angela E. Obongo, Yolanda Tolentino, Carolina Pessoa, Lea Miriam B.

Fonseca and Sergio L. Schmidt Federal University of the State of Rio de Janeiro, Brazil

Posters & Accepted Abstracts: J Nutr Disorders

Abstract:

Celiac Disease (CD) is an immune-mediated systemic disorder triggered by gluten and related prolamines in genetically predisposed individuals. Previous investigations using Single Photon Emission Tomography (SPECT) reported brain perfusion abnormalities in untreated CD patients with neuropsychiatric manifestations. Here, we described a case of a 31-yearold Caucasian woman who exhibited cerebellar and psychiatric dysfunctions. The patient underwent SPECT images before and after a Gluten Free Diet (GFD). There was an improvement in cerebellar perfusion accompanied by a remission of cerebellar manifestations. The patient�??s psychiatric symptoms did not change after 4 months and a half under a GFD. The maintenance of the psychiatric manifestations was related to the persistence of the hypoperfusion in frontal lobes. To our knowledge, this is the first case that shows the relationship between improvement in cerebellar perfusion and remission of cerebellar clinical manifestations in a CD patient under a GFD.

Biography :

Juliana Schmidt is a M.S student in neuroscience and has a bachelor’s degree in nutrition sciences. Julio Tolentino is an Assistant Professor of Internal Medicine and Ph.D student. Guilherme Schmidt is a neurologist and Ph.D student. Eunice Simões is a licensed neuropsychologist and Ph.D. student. Lea Fonseca is a full Professor of Nuclear Medicine. Sergio Schmidt is a Full Professor of Neurophysiology. Carolina Pessoa is an Associate Professor of Nuclear Medicine. Yolanda Tolentino is a gastroenterologist at Gaffrée e Guinle University Hospital. Angela Obongo has a bachelor’s degree in nutrition sciences and currently is a Ph.D student.

E-mail: julianaschmidtjaneiro@gmail.com