Clinical Microbiology: Open Access

An overview of Crimean Congo hemorrhagic fever in Iran

3^rd Global Microbiologists Annual Meeting

August 15-17, 2016 Portland, Oregon, USA

Sadegh Chinikar

Pasteur Institute of Iran, Iran

Posters & Accepted Abstracts: Clin Microbiol

Abstract:

Introduction: Crimean Congo Hemorrhagic Fever (CCHF) is a zoonotic viral infection. The route of transmission is through the bite of infected ticks, handling of infected blood or organs of livestock and nosocomially. After emerging of CCHF in Iran in 1999, it was considered as a major public health problem. Methods: Sera samples from CCHF probable cases and domestic animals were collected from different provinces of Iran and transferred to the Arboviruses and Viral Hemorrhagic Fevers Laboratory (National Ref. Lab); Pasteur Institute of Iran. Samples were analyzed by ELISA and RT-PCR tests. Results: Males were the major infected gender for CCHF infection and livestock related professions considered among high risk factors for acquiring CCHF infection. The human disease has been seen in the majority of provinces of Iran (27 out of 31). The main human foci of the disease was Sistan-va-Baluchistan province in southeast of Iran. Phylogenetic investigations on CCHFV sequences obtained from human and tick samples showed that clade IV (Asia-1 and 2), clade V (Europe) and clade VI (Greece) are circulating genomic variants of CCHFV in Iran. Conclusion: CCHF is one of the most important viral emerging zoonotic diseases in Iran. Since understanding the molecular epidemiology of CCHFV, it is an essential action to develop and implement surveillance strategies for its control, on-going surveillance and molecular epidemiology of CCHFV is noteworthy.

Biography :

Email: sadeghchinikar@yahoo.com