Surface Engineering of the RNA Coliphage QB to Display Plasmodium Falciparum Derived Asexual Blood Stage Antigens UB05 and Merozoite Surface Protein 3

Ghislain D. Njambe Priso^4,5, Godwin W. Nchinda^20*, Chae Gyu Park^18,19, Lazare Kaptue¹⁷, Wilfred N. Mbacham^4,14,16, Eric A. Achidi⁶, Charles O. Esimone¹⁵, Rosette Megnekou^5,14, Malachy I. Okeke¹³, George O. Chukwuma^4,12, Dieudonné Ndjonka¹⁰, Anna Gutiérrez¹¹, Rosario Garcia¹¹, Alain Bopda Waffo^1,2,3*, Georgia Ambada^4,5, Doline Takoua¹⁰, Arinze S. Okoli⁹, Jules N.C. Assob⁶, Colince J. Tchadji^4,5, Swapnil Bawage^1,2, Carrie A. Sanders¹, Apeh A. Ngoh^4,8, Loveline N. Ngu^4,7, Herve F. Ouambo^4,6 and Abel Lissom^4,5

¹Department of Biological Sciences/College STEM 1627 Hall Street Montgomery, AL, USA

²Center for Nano Biotechnology Research, 1627 Harris Way Montgomery, AL, USA

³Microbiology Program, Department of Biological Sciences, College of Science, Technology, Engineering and Mathematics, Alabama State University, Montgomery, AL, USA

⁴Laboratory of Vaccinology/Biobanking, CIRCB, Cameroon

⁵Department of Animal Biology and Physiology, University of Yaoundé I, Cameroon

⁶Department of Medical Laboratory Sciences, University of Buea, Cameroon

⁷Department of Biochemistry, University of Yaoundé I, Cameroon

⁸Department of Biomedical Sciences, University of Dschang, Cameroon

⁹GenØk - Centre for Biosafety, Tromsø, Norway

¹⁰Department of Biomedical Laboratory Sciences, University of Ngaoundere, Cameroon

¹¹Centre de Santé Catholique de Bikop, Cameroon

¹²Department of Medical Lab Sciences, Nnamdi Azikiwe University, Awka, Nigeria

¹³Molecular Inflammation Research Group, Department of Medical Biology, Faculty of Health Sciences, UiT The Arctic University of Norway, N-9037 Tromsø, Norway

¹⁴The Biotechnology Center, University of Yaoundé I, Cameroon

¹⁵Department of Pharmaceutical Microbiology and Biotechnology, Nnamdi Azikiwe University, Awka, Nigeria

¹⁶The Department of Biochemistry and Physiology, Faculty of Medicine, University of Yaoundé I, Cameroon

¹⁷Université des Montagnes, Bangangté, Cameroon

¹⁸Laboratory of Immunology, Brain Korea 21 PLUS Project for Medical Science, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea

¹⁹Laboratory of Cellular Physiology and Immunology and Chris Browne Center for Immunology and Immune Diseases, The Rockefeller University, New York, NY 10065, USA

²⁰Department of Biochemistry, University of Dschang, Cameroon