Department of Pharmacology
University of North Texas, USA
Estrogens as neuroprotants against ischemic stroke: Neuroprotective agents and strategies have been studied for years and appear to be effective in a variety of preclinical stroke models. One of the major focuses in basic and in clinical research in the last decade has been related to the activities of estrogens. My research focuses on the neuroprotective effects of estrogens and related analogues, using rodent stroke models. My research has demonstrated that 17β-estradiol and several estrogen analogues exert neuroprotective effects on ischemia-reperfusion injury.