Journal of Clinical and Medical Sciences

Department of Clinical and Medical Sciences, King Edward Medical University, Lahore, Pakistan

Publications

• Research Article   
  Detection of Aminoglycoside Resistance Genes in Clinical Isolates of Acinetobacter baumannii
  Author(s): Sumbal Shahzadi*
  
  Acinetobacter baumannii is an emergent nosocomial, gram negative, coccobacilli pathogen that have ability to quickly acquire resistance against multiple antibiotics. Aminoglycoside is class for antibacterial drugs used for pathogenic organism and causes protein synthesis inhibition, irreversible attachment on ribosomal binding site and enzymatic degradation. A. baumannii has acquired resistance against aminoglycosides using multiple genes which produces aminoglycosides modifying enzymes for resistance. The aim of this study was to investigate the prevalence of gene encoding for three different aminoglycoside-modifying enzymes in A. baumannii. 50 strains of A. baumannnii were collected from Mayo Hospital, Services Institute of Medical Sciences and Children Hospital and Institute of Child Health. These strains were characterized by performing biochemi.. View more»
  

  DOI: 10.35248/2593-9947.25.9.314

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