Siya Kumari

Department of Periodontology, Career Post Graduate Institute of Dental Sciences and Hospital, Lucknow, Uttar Pradesh, India

  • Review Article   
    The Multiple Obscure Findings of Gingival Fibromatosis: A Review
    Author(s): Zeba Rahman Siddiqui*, Akanksha Singh, Siya Kumari and Srashti

    Gingival Fibromatosis (GF) is a slowly progressive, benign and rare disorder characterized by diffuse or local fibrous growth of gingiva. Hereditary Gingival Fibromatosis (HGF), which is usually an autosomal dominant trait, is the most common form. The attached gingiva, marginal gingiva and the interdental papilla is affected. In severe condition functional, periodontal, aesthetic and psychological problems may occur. Histopathology shows epithelial acanthosis and atypically abundant inflammatory infiltrates distributed in the sub-epithelial and connective tissue. The pathophysiology of gingival fibromatosis comprises excessive accumulation of extracellular matrix proteins. Mutation in the Son-of-Sevenless-1 (SOS-1) gene has been suggested as genetic attribute of hereditary gingival fibromatosis. To stabilize the long-term outcomes and alleviate suffering of adver.. View more»

    DOI: 10.35248/2684-1320.22.8.175

    Abstract HTML PDF