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Sahar Sadat Lalehzar
Department of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Publications
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Research Article
Evaluation of the Effectiveness of Nano-Hydroxyapatite Particles in Wound Healing in an Animal Study
Author(s): Sahar Sadat Lalehzar*, Rokhsareh Meamar, Ardeshir Talebi and Mehrafarin Fesharaki
Background: The main activity of the skin is to create a protective barrier against damage. Loss of the skin due to injury or disease and failure to regenerate the affected area may result in disability, infection, or even death. We conducted the animal study to evaluation of the effectiveness of nano-hydroxyapatite particles in wound healing. Method: This animal study performed in Isfahan university of medical science animal lab. Experiments were performed on 30 wistar in 5 groups. Biopsies 5 mm × 5 mm were obtain of abdominal, and were transferred to the cell culture laboratory into the Phosphate Buffer Saline (PBS). The cell proliferation was determined using the colorimetric MTS assay. The type and approach of this animal study is to create a deep skin wound and try to treat the wound with drug (nano hydroxyapatite 10%, nano hydrox.. View more»