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Jitendra Kumar
Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi, India
Publications
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Perspective
A Prospective: Hepatitis B Virus X Protein could be a Therapeutic Target for the Cure of Hepatitis B Virus Infection
Author(s): Purnima Tyagi, Akhilesh Kumar Saini and Jitendra Kumar*
Cirrhosis and hepatocellular cancer are linked to chronic hepatitis B infection. Virus replication necessitates the HBx (Hepatitis B Viral protein). Therapeutic targeting of Hepatitis B Virus (HBV) infection via its protein X (HBx) has emerged as a promising strategy for combating HBV. This article examines the prospective benefits and difficulties of targeting HBV infection with HBx, highlighting its implications for future therapeutic interventions. HBx-targeted therapies have the potential to revolutionise the treatment landscape for chronic HBV infection by interfering with viral replication and reducing HBx-induced pathogenesis. To completely realise the potential of HBx-targeted therapies, challenges such as HBx variability, off-target effects, and successful clinical translation must be addressed. Collaboration among researchers, clinicians, and policymaker.. View more»