Biology and Medicine

Department of Life Sciences, Hebrew University of Jerusalem, Jerusalem, Israel

Publications

• Research Article   
  Enhancing Genetically Engineered Escherichia coli Bioreporters for the Detection of Buried TNT-based Landmines
  Author(s): Eden Amiel*
  
  TNT (Trinitrotoluene) based buried landmines are explosive devices consisting of mainly 2,4,6-Trinitrotoluene (2,4,6-TNT), but also a 2,4-dinitrotoluene (2,4-DNT) impurity. It is reported that some 2,4-DNT impurity vapors slowly leak through land mine covers and into the soil above them, making this compound a potential indicator for the presence of buried landmines. There are several approaches to identify the presence of chemicals in the environment, one of which is based on a microbial detection system. This approach was previously used to address the challenge of remotely identifying buried landmines by applying genetically engineered microbial whole cell biosensors capable of sensing trace signatures of the explosive compound 2,4,6-TNT and its degradation product, 2,4-DNT. Upon exposure to 2,4-DNT, the genetically engineered bacterial reporter strains, contai.. View more»
  

  DOI: 10.35248/0974-8369.23.15.604

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