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David Vollmer
4Life Research LLC., Sandy, Utah, United States of America
Publications
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Research Article
Two Natural Product Compositions Improve Lifespan and Healthspan in Caenorhabditis Elegans by Targeting the Hallmarks of Aging
Author(s): Lawry Han and David Vollmer*
Aging has been increasingly recognized as a global health burden. Current aging research suggests that preventative strategies may increase both lifespan and healthspan. Many natural compounds or natural products have demonstrated promising antiaging benefits and gained popularity in aging research. The present study evaluated two compositions comprised of nicotinamide mononucleotide, quercetin, alpha ketoglutarate, white button mushroom extract (standardized to spermidine), Transfer Factor (TF) (extracts from cow colostrum and chicken egg yolk) with or without milk thistle fruit extract (standardized to silybin) and apigenin for their antiaging effect in Caenorhabditis elegans (i.e., C. elegans). The active ingredients included in the two compositions were screened for their senolytic effects on cell viability of irradiated human umbilical vein endothelial cells. To further explore t.. View more»