Tahmeed Ahmed
Centre for Nutrition and Food Security,
icddr,b 68 Shaheed Tajuddin Ahmed Sarani Mohakhali, Dhaka-1212
Bangladesh
Review Article
Vitamin B12 Deficiency in Pregnancy and Lactation: Is there a Need for Pre and Post-natal Supplementation?
Author(s): Towfida J Siddiqua, Lindsay H Allen, Rubhana Raqib and Tahmeed Ahmed
Towfida J Siddiqua, Lindsay H Allen, Rubhana Raqib and Tahmeed Ahmed
This article reviews vitamin B12 (B12) status and deficiency during pregnancy and lactation, its effect on
pregnancy, and the health of the offspring, with the aim to underscore the need for a sustainable strategy to improve maternal and infant vitamin B12 status of low and middle income countries. Vitamin B12 is a basic nutrient required for maintenance of normal erythropoiesis, cell reproduction, nucleoprotein and myelin synthesis. B12 deficiency is associated with adverse pregnancy outcomes and neurodevelopmental morbidity during infancy. Very few studies have indicated that B12 deficiency may contribute to altered immune responses in animals and humans. Additionally, no studies have shown modulation of infant motor development in response to maternal B12 supplementation. Despite the high global prevalence of B12 deficiency and its serious effects on pregnant women and offsp.. View More»
DOI:
10.4172/2161-0509.1000142