PMC/PubMed Indexed Articles
Indexed In
- Open J Gate
- Genamics JournalSeek
- SafetyLit
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- Publons
- Geneva Foundation for Medical Education and Research
- Euro Pub
- Google Scholar
Useful Links
Share This Page
Journal Flyer
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Nikitchenko Yu V
Nikitchenko Yu V
Ukraine
Publications
-
Research Article
Overeating in Early Postnatal Ontogenesis Forms Metabolic Memory and Reduces Lifespan
Author(s): Bozhkov AI, Nikitchenko Yu V and Al-Bahadly Ali MMBozhkov AI, Nikitchenko Yu V and Al-Bahadly Ali MM
We investigated the role of metabolic memory in a choice of strategies for adaptation to stress influences. We used a model of rat overeating in early ontogenesis from birth to 21 days of life and investigated the maintenance of formed metabolic pattern in later ontogenesis. The following characteristics were measured: somatometric indicators, resistance of animals to a temperature stress of 32ᵒC, thyroxin and triiodothyronine content in blood serum, NO-synthase activity, the content of lipid hydroperoxides and antioxidant enzymes in different organs in animals of 3, 20 and 31 months of age under standard conditions of maintenance in control animals and after overeating in the early ontogenesis. It is shown that the metabolic pattern formed on the background of overeating from birth to 21 days remains until the later stages of ontogeny. The forming metabolic pattern is characterized.. View More»
DOI: 10.4172/2167-7182.1000309