Journal of Clinical & Experimental Pharmacology

Marco Manfredi

Publications

• Review Article
  Which Treatment in Helicobacter pylori Infection?
  Author(s): Marco Manfredi, Barbara Bizzarri, Elisabetta Manzali, Alessandro Fugazza, Pierpacifico Gismondi and Gian Luigi de’AngelisMarco Manfredi, Barbara Bizzarri, Elisabetta Manzali, Alessandro Fugazza, Pierpacifico Gismondi and Gian Luigi de’Angelis
  
  For many years in Helicobacter pylori-positive patients, the most used eradication regimen has been the triple therapy, consisting by the association of two antibiotics usually chosen between amoxicillin, clarithromycin and metronidazole. In recent years because of the increasingly resistance of this therapy, several options have been used. The most innovative regimen is sequential therapy, but maybe bismuth-containing quadruple therapy is the more frequently used worldwide. Other effective treatments are concomitant therapy or quinolone-containing triple therapy. Moreover, further approaches have been developed such as the hybrid therapy or the quadruple in which three antibiotics are included in a single capsule. The therapeutic approach for second-line therapy should be based on the regimen used in the first-line treatment trying to obtain the best eradication rat.. View More»
  DOI: 10.4172/2161-1459.1000139

  Abstract PDF