Journal of Clinical & Experimental Pharmacology

Mahmood Ameen Abdulla

Publications

• Research Article
  Leaves Extract of Muntingia Calabura Protects Against Gastric Ulcer Induced by Ethanol in Sprague-Dawley Rats
  Author(s): Ibrahim Abdel Aziz Ibrahim ,Mahmood Ameen Abdulla ,Siddig Ibrahim Abdelwahab *,Fouad Al-Bayaty ,Nazia Abdul MajidIbrahim Abdel Aziz Ibrahim ,Mahmood Ameen Abdulla ,Siddig Ibrahim Abdelwahab *,Fouad Al-Bayaty ,Nazia Abdul Majid
  
  Aim: Muntingia calabura is a medicinal plant used popularly known in Malaysia against various diseases including peptic ulcer. This study was performed to evaluate the gastroprotective effect of ethanolic extracts of Muntingia calabura Leaf Extract (MCELE) against ethanol-induced gastric mucosal injury in experimental rats. Methods: The rats were divided into four groups respectively pre-treated orally with Carboxymethyl Cellulose (CMC) solution (ulcer control groups), omeprazole 20 mg/kg (reference group), 250 and 500 mg/kg of MCELE (experimental groups) one hour before oral administration of absolute ethanol to generate gastric mucosal damage. After an additional hour, the rats were sacrificed and the ulcerated areas of the gastric walls were determined. Results: The ulcer control group exhibited severe mucosal injury,.. View More»
  DOI: 10.4172/2161-1459.S5-004

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