Journal of Neonatal Biology

Mahendra Singh

Publications

• Research Article
  Can Higher PEEP and FiO₂ with Bubble CPAP Reduce Need for Invasive Ventilation in Preterm Babies with Respiratory Distress Syndrome?
  Author(s): Lata Bhat, Kavita Khanijo, Supriya Bisht, Amit Wadhawan, Mahendra Singh and Vishnu Bhat Lata Bhat, Kavita Khanijo, Supriya Bisht, Amit Wadhawan, Mahendra Singh and Vishnu Bhat
  
  Objectives: To evaluate the clinical course and outcome in preterm babies with RDS using higher PEEP and FiO2 as appropriate on bubble CPAP as the primary mode of respiratory support. CPAP failure and oxygen requirement by 28 days of life were primary outcome. Incidence of pneumothorax, hypotension, NEC, IVH and ROP and survival till discharge were thesecondary outcomes measured. Method: Preterm babies (gestation 26 to 36 weeks) admitted to tertiary level NICU (both inborn and outborn) with RDS were managed with bubble CPAP as a primary mode of respiratory support. Higher pressure upto 8-10 cm of water and FiO2 upto 80-100% was given (if required) during CPAP. Results: Total 73 neonates were studied, out of which 52% received antenatal steroids and 54.8% received surfactant. Overal CPAP success rate was 95.9% with succe.. View More»
  DOI: 10.4172/2167-0897.1000205

  Abstract PDF