Indexed In
- Open J Gate
- Genamics JournalSeek
- Academic Keys
- JournalTOCs
- ResearchBible
- Electronic Journals Library
- RefSeek
- Hamdard University
- EBSCO A-Z
- OCLC- WorldCat
- Proquest Summons
- SWB online catalog
- Virtual Library of Biology (vifabio)
- Publons
- MIAR
- Euro Pub
- Google Scholar
Useful Links
Share This Page
Journal Flyer
Open Access Journals
- Agri and Aquaculture
- Biochemistry
- Bioinformatics & Systems Biology
- Business & Management
- Chemistry
- Clinical Sciences
- Engineering
- Food & Nutrition
- General Science
- Genetics & Molecular Biology
- Immunology & Microbiology
- Medical Sciences
- Neuroscience & Psychology
- Nursing & Health Care
- Pharmaceutical Sciences
Magnus Ingelman-Sundberg
Magnus Ingelman-Sundberg
Karolinska Institutet,
Nanna Svartz väg 2, SE- 171 77 Stockholm
Sweden
Publications
-
Review Article
Pharmacogenomics of Cytochrome P450 Dependent Metabolism of Endogenous Compounds: Implications for Behavior, Psychopathology and Treatment
Author(s): Anna Persson and Magnus Ingelman-SundbergAnna Persson and Magnus Ingelman-Sundberg
Mood and anxiety disorders are a major burden to the society today but still the pathophysiology behind these disorders is largely unknown and the pharmacotherapy available today is far from sufficient, with relatively low remission rates. Recent results regarding the action of CYP2C19 and CYP2D6 in the CNS suggest associations between suicidality, anxiety and other stress-related disorders and such CYP enzyme polymorphisms. Knowledge about the CNS specific action of these enzymes might in the future provide an increased understanding of the pathogenesis and pathophysiology of these disorders. Here we present an update of the research carried out in human and animal models with focus on the roles of CYP2C19 and CYP2D6 for brain development and function mediated by the metabolism of endogenous compounds. .. View More»
DOI: 10.4172/2153-0645.1000127