Gouadoa I
Cameroon
Research Article
Effect of Combined Dietary Supplementation of Telfairia Occidentalis Leaves and Citrulus Colocynthis Seeds on Fasting Glycemia, Glucose Tolerance and Body Weight in Wistar Rats
Author(s): Etoundi Omgba BC, Palla Nyamena CL, Manz Koulea CJ, Gouadoa I
Etoundi Omgba BC, Palla Nyamena CL, Manz Koulea CJ, Gouadoa I
Though medical assistance can be given to diabetic patients, dietary care is highly explored. This work aimed at studying the effects of dietary supplementation of uncooked Telfairia occidentalis leaves combined with Citrulus colocynthis seeds on blood glucose level in Wistar rats. A phytochemical screening was realized on T.occidentalis ethanolic and hydroethanolic leaves extracts, and their acute toxicity was studied in rats. The effect of their combined dietary supplementation on glycemia and body weight was studied in rats receiving carbohydrate enriched diet during 28 days. Three test groups received 10% Telfairia occidentalis leaves, 10% C.colocynthis and a mixture of 5% T.occidentalis leaves and 5% C. colocynthis respectively. Glibenclamide (0.03 mg/kg b.w) was used as reference drug.
Glucose tolerance was tested at the end of supplementation period. The presence of t.. View More»
DOI:
10.4172/2161-0509.1000209