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Ernest N Anyabolu
Ernest N Anyabolu
Department of Medicine, Imo State University Teaching Hospital, Orlu,
Nigeria
Publications
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Research
Variable Influencing Parameters of Different Levels of Immunosuppression in HAART-naive HIV Subjects in Nigeria
Author(s): Ernest N Anyabolu Ernest N Anyabolu
Background and Objectives: Varying degrees of immunosuppression may be observed in human immunodeficiency virus (HIV) infected subjects. This study sought to evaluate the factors which might influence different levels of immunosuppression in this group of subjects. Methodology: Immunosuppression, defined as CD4<500 cells/ml, was evaluated in treatment-naïve HIV subjects. Body mass index (BMI), 24 h urine creatinine (24HUCr), 24 h urine protein (24HUP), creatinine clearance (ClCr), hemoglobin (Hb) and CD4 cells count were determined and the data compared among the subjects who have different levels of immunosuppression, defined here as mild for CD4 350-499 cells/ml, moderate for CD4 200-349 cells/ml and severe for CD4<200 cells/ml. Results: CD4 cells count 200-349/ml was prevalent in 31.3%, CD4 350-499/ml.. View More»
DOI: 10.4172/2327-5073.1000285