Journal of Food Processing & Technology

Abstract

Vitamin supplements and nutrition: Impact on the urine fluorescence spectrum

Praveen Chalissery, Christian Homann* and Ronald Sroka

Food, vitamins as well as health conditions can influence the color of human urine, which might affect the urine fluorescence spectrum. As fluorescence spectroscopy of human urine could be used as diagnostic tool in the medical field, for example as a screening method for cancer or porphyria through the measurement of Coproporphyrin III (CPIII), altered urine color could lead to misinterpretation and false diagnostic results. So, the investigation of vitamin supplements and food items on the urine fluorescence spectrum could prevent misinterpretation of findings. Among the investigated substances, such as water- and fat-soluble vitamins and food, intake of vitamin B2 had noticeable effect on the urine fluorescence spectrum. Interference with the recovery rate of CPIII was not found among any investigated substance. Therefore, it is recommended to avoid vitamin B2 supplementation before fluorescence spectroscopy on human urine is used as diagnostic procedure. With regard to CPIII as target marker, CPIII concentrations in urine could be accurately determined in all tested cases.

Published Date: 2025-11-22; Received Date: 2024-10-22