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Haemostasis is a process of formation of clot bleeding to stop bleeding that is the first stage of wound healing. Hemostasis occurs when blood cell is present outside of the body or blood vessels. Hemostasis has three major steps: 1) vasoconstriction, 2) temporary blockage of a break by a platelet plug, and 3) blood coagulation, or formation of a fibrin clot.

Haemostasis is the body's normal physiological response for the prevention and stopping of bleeding/haemorrhage results in the blocking of any vascular breach. Haemostasis involves a coordinated effort between platelets and numerous blood clotting proteins resulting in the formation of a blood clot and subsequent stopping of the bleed. The most common Haemostasis disorders, Von Willebrand disease, hemophilia, and Factor V Leiden thrombophilia, all involve defects in the amount or activity of factors involved in coagulation.

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BMC blood disorders, American journal of Haematology, Blood Cells, Molecules and Diseases

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