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Transcriptomic signatures induced by Zn nanoparticle in Hydra magnipapillata
International Conference and Exhibition on Nanotechnology & Nanomedicine
March 12-14, 2012 Omaha Marriott, USA
Seonock Woo and Seungshic Yum
Accepted Abstracts: J Nanomedic Nanotechnol
Abstract:
Hydra is a Cnaidarian model, which is the most primitive multicellular animal showing tissue organization. Diverse approaches with hydra have been accelerated since its genome and EST database was reported in 2010. We extracted 17741 genes from Hydra magnipapillata genome and EST database (http://hydrazome.metazome.net/cgi- bin/browser/hydra) and established hydra oligoarray to investigate its transcriptomic signatures induced by Zn nanoparticle. We examined 50% lethal concentration to ZnO nanoparticles first and exposed hydra to ZnO nanoparticles at 1/50 of LC50. We detected unique and diverse transcriptome of hydra induced by exposure to ZnO nanoparticles and reported the categorized genes showing significant transcriptional changes