Biochemistry & Analytical Biochemistry

Oral glucose tolerance in diabetic male albino rats fed with a diet incorporated with Vernonia amygdalina leaves and Treculia africana seeds at 20% and 30%

Global Congress on Biochemistry, Glycomics & Amino Acids

December 08-09, 2016 San Antonio, USA

Abaleke Innocent Onyedikachi

Michael Okpara University of Agriculture, Nigeria

Posters & Accepted Abstracts: Biochem Anal Biochem

Abstract:

The present study evaluated the oral glucose tolerance in diabetic male albino rats fed with a special diet incorporated with Vernonia amygdalina leaves at 20% and boiled Treculia Africana seeds at 30%. Thirty male albino rats that fall within same weight range were randomized into two groups, control and test group, respectively. Diabetes was induced by the use of streptozotocin, the control group was fed with normal vital growers mash while the test group was fed with the special diet incorporated with Vernonia amygdalina leaves at 20% and boiled Treculia africana seeds at 30% for 28 days. Weekly oral glucose tolerance test was done on both the control and test groups and fasting blood sugar test. The result obtained showed improved glucose tolerance at first, second, third and fourth week since the blood glucose returned to baseline glucose concentration (p>0.05) in test group compared to control at 30 minutes, 60 minute, 90 minutes and 120 minutes after glucose load of 1g/kg. The result also showed that the fasting blood sugar of the test group was significantly (p>0.05) lower than that of the control group. The study suggests that this special diet could improve glucose tolerance and help control blood sugar in diabetic condition.

Biography :

Abaleke Innocent Onyedikachi is a graduate of Biochemistry from Michael Okpara University of Agriculture, Umudike Abia State of Nigeria. He is currently pursuing his Master’s degree in Nutritional Biochemistry. He has presented a research paper during the conference of Nigerian Society of Biochemistry and Molecular Biology held in the year 2012 at University of Calabar Cross river State Nigeria.

Email: abalekeinnocent@gmail.com