Oral Health and Dental Management

Optical biopsy:The future vision of clinical non-invasive modalities in diagnosis of oral squamous cell carcinoma (OSCC)

International Conference and Exhibition on Dentistry

March 18-20, 2015 Dubai, UAE

Esam Omar

Posters-Accepted Abstracts: Oral Health Dent Manag

Abstract:

Oral squamous cell carcinoma (OSCC) has a remarkably high incidence worldwide, and a fairly serious prognosis, encouraging further research into advanced technologies for non-invasive methods of making early diagnoses, ideally in primary care settings. In this article, authorreviews advanced technologies for non-invasive methods of diagnosing OSCC by available studies of optical biopsy, the sensitivity and specificity of different optical biopsy technologies and the possibility of their use in the primary care setting. Optical biopsy, which uses the technology of spectroscopy, based on the nature of light-tissue interactions, can be used to detect changes at a sub-cellular level; thus, it provides information that may not be available with conventional histology with reliable sensitivity and specificity. It is clearly evident that screening and early detection of cancer and pre-cancerous lesions have the potential to reduce the morbidity and mortality of this disease. Optical biopsy is promising non-invasive method for diagnosing OSCC that are easy to perform clinically. It shows promising pathways for the future development of more effective prognosis.