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Molecular and cellular assays for screening and identifying potential novel phytochemical-based therapeutics
Annual Pharmaceutical Biotechnology Congress
May 16-17, 2018 Singapore
A Vieira
Simon Fraser University, Canada
Posters & Accepted Abstracts: Pharm Anal Acta
Abstract:
The use of medicinal plant extracts as well as purified phytochemicals and phytochemical combinations for pharmacotherapy is currently under investigation for a wide range of human diseases including infectious and chronic diseases. Such phytochemical compounds are typically screened through molecular and cellular assays and further evaluated in wholebody (e.g., animal) experimental model systems. High-throughput screening assays for identifying phytochemical-based pharmacotherapeutics will be presented, with an emphasis on one or more of the following potential applications: (1) Infectious diseases and modulation of the cellular internalization of the pathogen, (2) amyloidogenic diseases and disruption of cellular redox balance and (3) metabolic diseases such as type-2 diabetes and cellular energy metabolism. avvieira@sfu.ca