Pharmaceutica Analytica Acta

Measuring the rate of therapeutic adherence among outpatients with type-2 Diabetes mellitus in Dhule

5^th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems

March 16-18, 2015 Crowne Plaza, Dubai, UAE

Tabrej Mujawar1, P H Patil1 and Mohammed Rageeb2

Posters & Accepted Abstracts: Pharm Anal Acta

Abstract:

The support of therapeutic adherence is considered as an essential component of pharmaceutical care practice and patient healthcare. It has been shown that even with effective methods of treatment, 50% of diabetic patients fail to reach the satisfactory glycemic control, which leads to accelerated development of complications and increased mortality. Clinical practice indicates that no improvement of metabolic control is possible without patients? adherence to medications. This study sought to examine the rate of medication adherence and different factors affecting it among type 2 diabetic patients in Dhule. A total of 216 type 2 diabetic patients who fulfilled the inclusion criteria were recruited in the current study. Adherence to the treatment was evaluated during patients? in the Outpatient Medicine Department at SBHGMC in Dhule (MS) The medication adherence has been assessed during a personal interview with each patient using a multiple choice graded questionnaire. In the study population, the adherence rates for medication, dietary/exercise and appointment were observed to be suboptimal. The most important social factors that were significantly affecting adherence rate to the prescribed oral hypoglycemic agent(s) included marital status (P<0.01), family support (P<0.01), and socioeconomic level (P<0.01). Other patient factors that were significantly affecting therapeutic adherence were patient knowledge about the disease (P<0.01), patients? attitude and motivation about prescribed drugs (P<0.01), and regularity of patient self monitoring of blood glucose level (P<0.01). Among drug factors which found to affect significantly the rate of medication adherence are the number of drugs taken (P<0.05), difficulty of the drug regimen (P< 0.01), and the presence of drug side effects (P<0.01). Economical factor played an equally important role. Direct and indirect care costs in relation to patients? income were significantly affecting the rate of adherence to medication (P<0.01). Conclusions: Improvement with the adherence to oral hypoglycemic agent(s) may be achieved through continuing patient education about diabetes, enhancement of patients? economical levels as well as a reduction in the cost of medication. Pharmaceutical care has to be involved and pharmacists have to help chronically ill patients to take their medicines correctly for improving clinical outcomes.