Oral Health and Dental Management

Influence of blue light autofluorescence in the early detection of oral premalignant and malignant lesions

35^th International Conference on Dentistry & Dental Marketing

October 05-06, 2017 Las Vegas, USA

Dunia Wadeea Sabea

Al Iraqia University, Iraq

Scientific Tracks Abstracts: Oral Health Dent Manag

Abstract:

Background & Aim: Early detection of oral malignancies plays a very important role in the treatment process. The aim of our study was to investigate the efficacy of blue light induced autofluorescence in the early detection of oral malignant and premalignant lesions of the oral cavity using blue light irradiation- fluorescence detection device (VELscope Vx)® comparing it with incandescent light. Materials & Methods: 60 patients were subjected to full extra and intraoral examination involving the use of incandescent and fluorescent light for detection of premalignant and malignant lesions, after considering the patient's background and the possible risk factors, suspected regions were biopsied. Results: Tissue examination with incandescent light showed low prevalence of mucosal abnormalities even in patients with a suggestive background of possible malignant transformation, the overall prevalence was 0.75%. Using blue light autofluorescence together with above examination raised the prevalence up to 1.5% of which 80% where potentially premalignant dysplastic changes when biopsied. Conclusion: Using autofluorescence techniques is highly recommended for the early detection of oral premalignant and malignant lesions and should be always integrated to the routine oral examination taking the possible risk factors and the patient's background into consideration.

Biography :

Dunia Wadeea Sabea has earned her PhD from the University of Baghdad in 2003. She currently serves as the Dean of Faculty of Dentistry, Iraqi University, Iraq. She has also served as the Dean of Faculty of Dentistry in Anbar University in the past. Her research interest includes oral squamous cell carcinoma, its early detection and herbal therapy and also experimental methods of cancer researches.