Biochemistry & Analytical Biochemistry

Identifying the need of platelet transfusion for dengue epidemics in India

International Conference on Clinical Chemistry & Laboratory Medicine

October 17-18, 2016 Chicago, USA

Yogini Patel

Global Hospital & Research Centre, India

Scientific Tracks Abstracts: Biochem Anal Biochem

Abstract:

Critical shortage of platelets in the city has lead to preferential transfusion of platelets. 600 patients were tested for NS1, screened for platelets count, mean platelet volume (MPV), IGG and IGM. A significant difference in Chi Sq (p<0.5) value was observed in patients with low platelet count, high MPV, not associated with overt bleeding as compared with patients with low platelet count, normal mean platelet volume and overt bleeding. A regular follow up of platelet count test at six hourly interval revealed that the crisis period for an active dengue patient persists only for �??twenty four hours�?� and it can be easily overcome with simple intravenous (IV) saline transfusion for flushing and/or oral hydration. Based on clinical diagnosis of overt bleeding, the decisions on platelet transfusion can be taken. As a result, we can avoid transfusion in around 60% of patients who are tested positive for NS1 dengue parameters and thereby overcoming the platelet shortage in management of dengue in India.

Biography :

Yogini Patel has obtained her PhD in Applied Biology (Liver Disease in Hemophilia and Thalassemia with special reference to HIV AND HBsAg) during 1983-1989. She has received many certifications which include NABL Internal Auditor Certification from GOI India, Jaipur, ICH GCP Certification from Pharmacy College Mum University, Lead Assessor Course certification from NABH-GOI-Hospitals & NABH-GOI-Blood banks. She was the Joint Director of Blood Safety and Quality Assurance-MDACS from 2009-2010. She has also served as an Editorial Secretary for Indian Journal of Hematology and Transfusion Medicine. She is the recipient of many awards such as, Rotary International Vocational Excellence Award for Blood Transfusion Services, Dr L H Hiranandani and Dr A J Desai Award for Best Poster from Indian Society of Hematology and Transfusion Medicine-2001 and RD Birla Award in 2004 for research in presence of anti-hepatitis B core antibody in blood donors tested negative for HBsAg.

Email: dr_yoginipatel@yahoo.com