Oral Health and Dental Management

Effectiveness of coating acrylic resin dentures on preventing Candida adhesion

4^th Asia Pacific Congress & Expo on Dental and Oral Health

July 27-29, 2015 Brisbane, Australia

Aiman A Ali, Fahad A Alharbi and C S Suresh

Posters-Accepted Abstracts: Oral Health Dent Manag

Abstract:

Purpose: The aim of this study was to prevent the adhesion of C. albicans on acrylic resin dentures by modifying their surfaces. Materials & Methods: Ninety acrylic resin plates were divided into three groups. Group I: conventionally processed acrylic resin plates. Group II: plates painted with 2-Octyl Cyanoacrylate adhesive. Group III: plates painted with Adper Single Bond Adhesive. All specimens were immersed separately in containers filled with artificial saliva that contained C. albicans and then incubated for 11 days at 370C. Three methods of evaluation were used to count the adhered Candida: direct culture, slide count, and serial dilutions. Results: C. albicans in 1/10, 1/102, and 1/103 dilutions showed overgrowth in group I, while overgrowth was noted only with 1/10 dilution in group III. For group III, mean colony numbers of 123, 22, 3.4, and 0 were found for the 1/102, 1/103, 1/104, and 1/105 dilutions, respectively. Regarding the slide counts, group I showed a mean fungal count of 166 compared to 40 for group III with 1/10 dilution, 21 compared to 9 with 1/102 dilution, 8.6 compared to 0.7 with 1/103 dilution, and 1.2 compared to 0 with 1/104 dilution. No plates in group II showed any candidal colonies regardless of the method of evaluation (0%). These differences were statistically significant (p<0.0001). Conclusion: Coating the acrylic resin dentures with Adper Single Bond Adhesive was effective in reducing C. albicans adhesion to dentures, while coating with 2-Octyl Cyanoacrylate adhesive completely inhibited such adhesion.