Biochemistry & Analytical Biochemistry

Cytological-energetic principle examination of the extra-vascular body fluids, including the cerebrospinal fluid

International Conference on Clinical Chemistry & Laboratory Medicine

October 17-18, 2016 Chicago, USA

Petr Kelbich, A Hejcl, J Prochazka, E Hanuljakova, I Stanek, V Maly, A Karpyuk, E Svitilova and M Sames

Masaryk Hospital in �stí nad Labem, Czech Republic
J E Purkinje University, Czech Republic

Scientific Tracks Abstracts: Biochem Anal Biochem

Abstract:

An impairment of an organ system is usually associated with a local inflammatory response. It is projected into the composition of a particular extravascular fluid. Specification of a local inflammation is important for an accurate diagnosis of a particular organ. We use the cytological-energetic principle for the extravascular body fluids examination. The first step is specification of its cellular composition. The second step is the specification of local immunocompetent cells activation via the evaluation of glucose metabolism. We derived the so-called Coefficient of energy Balance (KEB): KEB=38-18(lactate)/(glucose). This parameter is calculated from molar concentrations of glucose and lactate in the extra-vascular fluid. Itâ??s defined as the theoretical average number of molecules of adenosine triphosphate produced from one molecule of glucose under given conditions in the particular compartment.

Biography :

Petr Kelbich has completed his MSc at the Faculty of Natural Sciences, Charles University in Prague in 1995 and received his PhD at the Faculty of Medicine in Hradec Králové, Charles University in Prague in 2015. He works as a Biologist and Specialist for the extravascular body fluids examination at the Department of Clinical Biochemistry, Masaryk Hospital in Ústí nad Labem in the Czech Republic. He has published more than 20 papers in peer-reviewed journals.

Email: petr.kelbich@kzcr.eu