Biochemistry & Analytical Biochemistry

Chemical basis of treating chemotherapy-induced neutropenia in pediatric ALL patients by chamomile oral drop

International Conference on Clinical Chemistry & Laboratory Medicine

October 17-18, 2016 Chicago, USA

Babak Daneshfard and Reza Sanaye

Shiraz University of Medical Sciences, Iran

Scientific Tracks Abstracts: Biochem Anal Biochem

Abstract:

Neutropenia is a blood disorder defined by a decrease in the absolute neutrophilic count (ANC) below the normal range. As a common complication of chemotherapy, it is associated with susceptibility to serious bacterial and fungal infections which could be life threatening. Matricaria chamomilla (Asteraceae), also called Baboone Shirazi in Traditional Persian Medicine (TPM) literature, is a globally used medicinal herb with a wide range of applications. Apigenin as one of the main components of chamomile is an antiinflammatory agent which suppresses prostaglandin E2. Moreover, it plays an anxiolytic role by reducing GABA-activated chloride currents. Apigenin has also shown anti-cancer effects in human cell lines making chamomile a safe affordable anti-cancer agent. Results of a pilot controlled clinical trials on pediatric ALL patients with chemotherapy induced neutropena revealed a significant increase in the number of white blood cells and neutrophils following 10 days consumption of chamomile oral drop. Such a beneficial complementary therapy would naturally decreases the need for Granulocyte Colony Stimulating Factor (GCSF) and its related complications in these patients.

Biography :

Babak Daneshfard has received his PhD from Shiraz University of Medical Sciences (SUMS). He has published more than 10 papers in reputed journals and has been serving as a Reviewer of CAM journals. He is also an expert in mind-body medicine.

Email: babakdaneshfard@gmail.com