Eiman A A Elshaygi
Al Jouf University, KSA
Posters & Accepted Abstracts: Biochem Anal Biochem
Statement of the Problem: Electrolyte and trace elements disturbances frequently occur with leukemia patients that complicate their management and prolong patientâ�?�?s hospitalization. This research work investigated the interrelationship among different types of leukemia with concentration of electrolytes and trace elements in Sudanese patients. Methodology & Theoretical Orientation: 201 subjects were included in the study; (79 control participants and 122 were suffering from leukemia). Patients were divided into four groups; acute lymphoid leukemia (ALL), acute myeloid leukemia (AML), chronic myeloid leukemia (CML) and chronic lymphoid leukemia (CLL) with some electrolytes and trace elements like zinc (Zn), copper (Cu), manganese (Mn) and cobalt (Co). Findings: Significant decrease in serum level of Cu, Mn and Co (p<0.05) was observed in all groups. Zinc and calcium showed lower levels in CLL, CML and ALL (p<0.05). The results also showed significantly higher serum level of Zn in AML group than CML group (p<0.05). Magnesium reported higher level in CML, AML and ALL (p<0.01). The concentration of Mg was significantly lower in CLL (p<0.05) compared to CML, AML and ALL patients. The concentration of sodium was significantly lower in CML than the ALL patients (p<0.05). There is no significant difference between the levels of Na, K and PO43- in leukemia patients and control. Conclusion & Significance: This study concluded that, leukemia patients in Sudan recorded significant decrease in serum levels of copper, manganese and cobalt. Most of them showed higher magnesium levels and lower concentration of zinc and calcium.
Eiman A A Elshaygi is serving as a Lecturer at Al-Jouf University, Saudi Arabia since 2009. Her expertise is in clinical research and had passion in improving the health and wellbeing.