Pharmaceutica Analytica Acta

A study of the effects of oral spray of papaya enzymes in patients with dysphagia and malnutrition with consideration to bacterial colonization and immunological response

5^th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems

March 16-18, 2015 Crowne Plaza, Dubai, UAE

Martha J P Karagiannis1 and Tom C Karagiannis2,3

Posters & Accepted Abstracts: Pharm Anal Acta

Abstract:

Rationale: Current practice indicates that at the discretion of the speech Pathologist patients experiencing dysphagic symptoms in association with saliva viscosity and dry mouth may be prescribed paw extract, pineapple or grape seed juice. Aims: To investigate the effects of papaya enzymes in patients with dysphagia and issues regarding saliva viscosity and dry mouth, to determine the association of microbiological and immunological outcomes with the clinical data from the study participants and to investigate quality of life of the participants and consider mental health wellbeing as a result of the consumption of papaya enzymes. Methods: 100 participants with dry mouth or viscous saliva were able to participate. Samples of mouth swabs and nasal swabs were collected to determine candida albicans, coliforms and flow rate of saliva. 100 of participants were completed a pre and post quality of life survey and objective measures for dry mouth were obtained. Results: 100% of participants reported improved quality of life, pleasant taste and a marked improvement regarding decreased thirst and dry mouth quality. Saliva flow rate increased for 100% of the participants with decreased saliva flow. The results of the mouth swabs also indicated that there was an improvement by reducing the amount of candida albicans and coliforms found in the mouth within a one week period as a result of spraying the papaya enzymes, therefore decreasing or eliminating oral thrush.