Oral Health and Dental Management

A case of Vander Woude Syndrome with rare phenotypic expressions

4^th Asia Pacific Congress & Expo on Dental and Oral Health

July 27-29, 2015 Brisbane, Australia

Anurag Tripathi1, Brijesh tiwari2, Shalini Gupta1 and Ranjit patil1

Posters-Accepted Abstracts: Oral Health Dent Manag

Abstract:

Objectives: To present a case of Vander Woude Syndrome with Rare Phenotypic Expressions. Case: A 12 year old male patient with complaint of drainage of fluid from depression on the lower lip reported in the Department of Oral Medicine and Radiology of King George Medical University Lucknow. The watery discharge was continuous and was aggravated during eating. Past surgical history revealed that the patient had undergone surgical correction of upper cleft lip and cleft palate at the age of 10 months. The family history did not reveal consanguineous marriage of his parents. According to his mother, the patient was born after a normal, full-term pregnancy with no exposure to radiation. The extra oral examination revealed surgical scar of the upper operated bilateral cleft lip and a median transverse pit on the lower lip filled with watery fluid. Intraoral examination of soft tissues showed a surgical scar of cleft palate correction. Dental examination revealed missing maxillary lateral incisors (hypodontia) and malpositioned teeth. An orthopantamograph disclosed bilateral palatal cleft and missing maxillary lateral incisors. On examination the left feet showed complete syndactyly of second and third toe while partial syndactyly of second and third toe was evident in right feet. The ultrasonography (USG) of lower abdomen revealed which was located in inguinal canal. The USG and colour Doppler examination further revealed that both testes were undescended & slightly reduced in volume with normal contour, echotexture and vascularity with no evidence of varicocele on any side. The clinical diagnosis of VWS syndrome was made on the basis of above findings. Conclusions: The current case have classical feature of VWS with some rare feature like undescended small testis and unreported finding of syndactyly of second and third toes adds on to the existing knowledge of VWS presentation.