Journal of Nutritional Disorders & Therapy

Vitamin Deficiency Implications in Muscle Weakness Patients

Emily Zohra^* Department of Nutrition, University of Toronto, Toronto, Canada
^*Correspondence: Emily Zohra, Department of Nutrition, University of Toronto, Toronto, Canada, Email:

Received: 27-Mar-2023, Manuscript No. JNDT-23-21332; Editor assigned: 29-Mar-2023, Pre QC No. JNDT-23-21332(PQ); Reviewed: 14-Apr-2023, QC No. JNDT-23-21332; Revised: 21-Apr-2023, Manuscript No. JNDT-23-21332(R); Published: 28-Apr-2023, DOI: 10.35248/2161-0509.23.13.238

Description

Muscle weakness is a condition where the muscles lose their strength and ability to perform normal activities. It can affect one or more muscles in the body and cause various symptoms such as difficulty walking, climbing stairs, lifting objects, or maintaining balance. Muscle weakness can have many causes, such as aging, injury, infection, inflammation, nerve damage, or genetic disorders. However, one of the possible causes that are often overlooked is vitamin deficiency. Vitamins are organic compounds that are essential for various biochemical processes in the body. They are obtained from food or supplements and are classified into two groups: water-soluble and fat-soluble. Water-soluble vitamins include vitamin C and the B-complex vitamins, which are easily absorbed and excreted by the body. Fat-soluble vitamins include vitamins A, D, E, and K, which are stored in the liver and fatty tissues and require bile and pancreatic enzymes for absorption. Vitamin deficiency occurs when the intake or absorption of a certain vitamin is inadequate to meet the body’s needs. This can result from poor dietary habits, malabsorption disorders, chronic diseases, medications, or increased requirements. Vitamin deficiency can affect various organs and systems in the body and cause a range of symptoms depending on the type and severity of the deficiency. One of the common symptoms of vitamin deficiency is muscle weakness.

There are several vitamins that play important roles in muscle strength and function. This vitamin is an antioxidant that protects the cells from oxidative stress and damage caused by free radicals. It also supports the immune system and helps prevent infections. Vitamin E deficiency can impair muscle function and cause muscle weakness, cramps, and degeneration. It can also affect the nervous system and cause loss of sensation, coordination, and reflexes. The signs and symptoms of vitamin deficiency can vary depending on the type and severity of the deficiency. If anyone experiences any of these signs and symptoms on a regular basis, then one should consult the doctor for a proper diagnosis and treatment. The best way to prevent vitamin deficiency is to eat a balanced diet that includes a variety of foods from different food groups. A final transcription complex is produced at the cell nucleus as a result of different transcription factors and biochemical processes modulating this ligand receptor contact. Vitamin D supplements cause quick alterations in calcium metabolism in muscle cells that are not explained by a slow hereditary mechanism.

For detecting ₂₅OHD (25-hydroxyvitamin D), there are two primary types of assays, the immune-based assay, which is frequently used in clinical practice, and the chromatographybased assay, which is frequently regarded as the gold standard in research. The use of various procedures by laboratories obviously results in a large deal of variation in test findings. Falls are a big issue for the elderly because they cause significant morbidity, higher mortality, and huge resource consumption in the healthcare system. A lack of vitamin D is linked to weak muscles, namely in the proximal muscular groups. As a result, walking speed is decreased, sit-to-stand times are prolonged, quadriceps strength is decreased, Short Physical Performance Battery (SPPB) scores are reduced, and the likelihood of falling is increased. Skeletal muscle cells have been discovered to contain Vitamin D Receptor (VDRs) that specifically bind 1,₂₅(OH)₂D in both human and animal models.

Conclusion

Vitamin E deficiency is rare in healthy people, but it can occur in people with malabsorption disorders, genetic diseases, or very low-fat diets. Magnesium mineral is involved in many biochemical reactions in the body, including energy production, muscle contraction and relaxation, nerve transmission, and electrolyte balance. Magnesium deficiency can cause muscle weakness, spasms, cramps, tremors, and twitching. It can also affect the heart rhythm and blood pressure. Magnesium deficiency can result from inadequate dietary intake, excessive losses through urine or sweat, or certain medical conditions or medications.