Influence of SLCO1B1 and SLCO2B1 Polymorphisms on Tacrolimus Pharmacokinetics and Clinical Response

Camila Alves¹, Claudia R Felipe², Alvaro M Nishikawa¹, Patricia C Salgado¹, Cristina Fajardo¹, Helio T Silva Jr², Jose Osmar M Pestana², Denize Zetchaku², Glaucio Spinelli², Nagilla Oliveira², Mario Hiroyuki Hirata¹, Rosario DC Hirata¹ and Alice C Rodrigues^3*

¹Faculty of Pharmaceutical Sciences, University of Sao Paulo, Brazil

²Hospital do Rim e Hipertensão, Fundação Oswaldo Ramos, Brazil

³Department of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, Brazil