Xiaoyan Jiang

Xiaoyan Jiang

Xiaoyan Jiang
Associate Professor, Deparment Medical Genetics
The University of British Columbia, Canada


Dr. Xiaoyan Jiang obtained a MD from Shanghai Second Medical University, Shanghai, China and a PhD (Molecular Biology) at McGill University, Montreal, Canada. She is now a Senior Scientist in the Terry Fox Laboratory of the BC Cancer Agency, an Associate Professor in the Department of Medical Genetics and an Associate Member in the Department of Medicine at the University of British Columbia.  She is also an Adjunct Professor at the Shanghai Institute of Medical Genetics of the Shanghai Jiao Tong University School of Medicine.  In 2005, she was awarded as a Michael Smith Foundation for Health Research Scholar.  She has presented at numerous international meetings, including a number of invited presentations, and is active as a research grant reviewer and an external (ad hoc) reviewer both in Canada and the USA. She is serving as an editorial member of several reputed journals and is a member of American Society of Hematology and International Society of Experimental Hematology since 1998.
Dr. Jiang’s research interests are focused on basic and translational leukemia research, particularly human chronic myeloid leukemia (CML).  The ultimate objective is to identify new, rationally designed, molecularly targeted therapies that will be more effective and less toxic than those presently available.  Recently, her research group has identified a novel AHI-1-BCR-ABL-JAK2 interaction complex that modulates BCR-ABL transforming activity and imatinib response of CML stem and progenitor cells.  Understanding the functions of this new interaction complex could lead to the development of new molecular targeted therapies.

Research Interest

Molecular and cellular mechanisms of oncogenes and tumor suppressor genes in the development of leukemia
Gene regulation
Leukemic stem cell biology
Basic and translational leukemia research
Genomic instability
Drug resistance