Vangelis G. Manolopoulos

Vangelis G. Manolopoulos

Vangelis G. Manolopoulos
Professor, Laboratory of Pharmacology, Medical School
Democritus University of Thrace, Greece


Dr Vangelis Manolopoulos is a full professor at the department of Pharmacology of Democritus University of Thrace Medical School in Alexandroupolis, Greece and at the Clinical Pharmacology Unit of the Academic General Hospital of Alexandroupolis. Ηe obtained a PhD from the Medical School of Patras University in 1991. Between 1992 and 1995 he did postdoctoral research at the Milwaukee Clinical Campus of the University of Wisconsin. Then he moved on to the department of Physiology of the Medical School of the Katholic University in Leuven, Belgium, where he was a research scientist between 1995 and 1998. Since 1998 Dr Manolopoulos has been teaching basic and clinical pharmacology to medical students at his university and since 2001 he has developed and teaches a course in Pharmacogenetics, one of the first to be introduced to the Medical School undergraduate curriculum worldwide. He has authored more than 80 indexed publications that have received more than 1500 citations, including a recent a recent publication in New England Journal of Medicine where he was the senior corresponding author (NEJM 369:2304, 2013). His current research interests include clinical applications of pharmacogenomics in drugs used for cardiovascular diseases, diabetes, anticoagulant therapy, asthma, and psychiatric diseases. In addition he has a long-standing interest in endothelial cell physiology and atherosclerosis. He was the Principal Investigator for Greece of the European Consortium for the pharmacogenetics of anticoagulation (EU-PACT). He has served for more than 10 years continuously at the Board of the Greek Society for Basic and Clinical Pharmacology and is currently its General Secretary. Between 2005-2011 he was the representative of Greece at the European Association for Clinical Pharmacology (EACPT). In Sept 2009 he organized the 8th Summer School of EACPT in Alexandroupolis. He is Vice President and member of the Board of the European Society for Pharmacogenomics and Theranostics (ESPT) and also chairs its Education and Courses Committee. In August 2012 he organized ESPT’s first Summer School in Ljubliana, Slovenia and in June 2014 he organizes a 2nd one in Rome.

Research Interest

His major research interests includes:
1. Clinical applications of pharmacogenetics and genomics of psychiatric, hypolipidemic, antiasthmatic, anticoagulant, and antidiabetic drugs.
2. Identification of novel genetic factors predisposing to atheromatosis, coronary artery disease, hypertension, diabetes, obesity, pediatric asthma, diabetic nephropathy, ischemic stroke.
3. Cardiovascular actions of Hydrogen Sulfide (H2S)
4. Analysis of cardioprotective and antineoplastic functions of natural compounds (pomegranate, asparagus officinalis)