Department of Biomolecular Sciences
University Carlo Bo of Urbino, Italy
Ferdinando Mannello is Assistant Professor of Diagnostic and Molecular Pathology at the Faculty of Sciences and Technologies of the University “Carlo Bo” of Urbino. He earned his PhD at University of Urbino, Italy. Currently, he is the Chair of the Cell Biology Unit and Breast Cancer Research Unit of the Section of Clinical Biochemistry at the Department of Biomolecular Sciences of the University of Urbino, Italy. He has published 130 Reviewed papers he was invited as speaker in 15 International Congresses and he was author of 3 book chapters. He has been teaching experience of more than 15 years. He served as President of the AULCT Urbino Association for the Fight Against Tumor. He was one of the members in the Italian Biological Association Society of Histochemistry Society of Clinical Biochemistry. He served as a reviewer of peer reviewed journals in the area of cell biology clinical biochemistry pharmacogenomic cancer research and stem biology. He was member of the Editorial Board of journals in the area of cancer research cell science and translational medicine. He received many awards like Award of the Society of Clinical Biochemistry 1996 and Dr. Susan Love Research Foundation Award 2005, 2007 and 2009.
Proteomic approach of identifying early breast cancer biomarkers (proteins, proteases, and hormones) in the fluid of the breast microenvironment (BCF and NAF), collected noninvasively from healthy and breast cancer patients; Study of signaling mechanisms regulating biomolecular expression and enzymatic activity of matrix metalloproteinases (MMP) and their tissue inhibitors (TIMP) in physio-pathological conditions (e.g., breast cancer, neural stem cell differentiation, chronic venous disease); Degradomic approach of analyzing proteinases circulating in biological fluids (NAF, plasma, urine), released from healthy and diseased tissues during neoplastic, inflammatory and degenerative processes; Biomolecular approaches of studying single cell analysis for a single patient pharmacogenomic.