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Zelalem Kiros Bitsue
Department of Infectious Diseases and Immunology, Founder and Director General US-AHO International, Dubai, UAE
Publications
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Review Article
Impact of Immunologic Discoveries on the Vaccine
Author(s): Zelalem Kiros Bitsue
The spike glycoprotein (S1) interacts with host cell epithelial Angiotensin-Converting Enzyme-2 (ACE-2) receptors. The nano-luciferase-based assay shows that the virus’s 1 protein has a strong binding affinity with the ACE-2 receptors. Reports illustrate the S-protein antigenic epitope of SARS-CoV-2 binds with the TLR4/ MD-2 complex by strong molecular bonding interactions. The pool of miRNA based studies shows that TMPRSS2 acts as promising regulators for the SARS-CoV-2 entry checkpoint. Recent report stated that the AT1R phosphorylates JAK2 in the lung cells, which activates STAT-3 transduction to the nucleus. Not only I discovered vaccine AZEE CRA 01, immune cell principles and methods of vaccination but also B cells have two components. B cells synthesis both MHC I, and MHC II. CD4 interacts with MQ, MHC II, CD8 Interacts with DC, MHC I, and B cells interacts with .. View more»