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Sethi Das Christu
Department of Medicine, Aster CMI Hospital, Bengaluru, India
Publications
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Research Article
Emerging Antifungal Resistance in Falco Species: A Novel Model for Human Medicine
Author(s): Sibi Das*, Sethi Das Christu, Christudas Silvanose, Ambili Binoy, Panagiotis Azmanis, Antonio Di Somma and Jibin V Gladston
Antifungal resistance is a growing concern in the medical community, as fungal infections are becoming increasingly difficult to treat. In this study, Falco species were used as novel models for studying antifungal resistance since aspergillosis, a fungal disease is common in falcons. The most isolated fungi in this study were A. fumigatus, A. flavus, A. niger, and A. terreus, all of which can cause aspergillosis in falcons. Isavuconazole, posaconazole, and voriconazole had the lowest MICs among the drugs tested, suggesting that they may be effective treatment options. However, this study showed that 34% of the isolates were resistant to itraconazole, which is an increase from 21% in 2006. There is no resistance to voriconazole found in 2006 and 2011, but a 9% resistance rate was noted in 2022. Similarly, there is no resistance to posaconazole and is.. View more»