Journal of Bioequivalence & Bioavailability

Department of Bioanalytical, Bio-Prospera Clinical Research Pvt. Ltd, Maharashtra, India

Publications

• Research Article   
  Comparative Bioavailability Study of Ultra Q 300 and COQ300 Coenzyme Q10 in Healthy Adults.
  Author(s): SM Rahman, Honey Qureshi, Poorneshwar Sawant, Sunil Kulkarni, Ravindra Mote* and Parikshit Champanerkar
  
  Purpose: In this study, two Coenzyme Q10 (CoQ10) formulations-Ultra Q 300 (test product) and other brand having similar composition (reference product)-were compared for bioavailability in healthy adult volunteers under fasting condition. Evaluating the safety and tolerability of a single oral administration of Ultra Q 300 at a dose of 300 mg was the secondary objective.  Methods: Fourteen healthy male volunteers between the age range of 18 and 45 participated in an open-label, randomized balanced, two- treatment, two- sequence, two- period, two-way crossover bioavailability research. During a 15-day washout interval in between doses, participants received a single 300 mg dosage of either Ultra Q 300 or other brand having similar composition while fasting. To assess Pharmacokinetic (PK) characteristics, such as Cmax and Tmax, 25 blood s.. View more»
  

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