Biochemistry & Analytical Biochemistry

Department of Biochemistry, University of Dschang, Cameroon

Publications

• Research Article   
  Acute and Sub-Chronic Toxicity Evaluation of Triplotaxis stellulifera (Benth.) Hutch and Crasssocephalum bougheyanum C.D . Adams Methanol Extract on Mice
  Author(s): Nfozon JN, Tume C*, Kdjo N, Boyom FF, Leonard SF, Dzoyem JP and Metinou S
  
  Background: Triplotaxis stellulifera and Crasssocephalum bougheyanum are two medicinal plants used in traditional medicine but little information are available on them. The objective of this study was to evaluate oral acute and subchronic toxicity of methanol extract of Triplotaxis stellulifera and Crasssocephalum bougheyanum. Methods: Acute toxicity was evaluated in mice by administrating a single dose of 5000 mg/kg body weight of tested extract. The sub-chronic toxicity was conducted by orally administering methanol extract of Crasssocephalum bougheyanum and Triplotaxis stellulifera at doses of 7.93, 23.8, 71.4, 214.2 mg/kg b.w respectively for 28 days in four groups of mice. Toxicity signs, Body and vital organ weights; serum, hematological and biochemical parameters were monitored dur.. View more»
  

  DOI: 10.35248/2161-1009.19.8.385

  Abstract HTML PDF